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reviewed thirty-five phase 3 randomized clinical trials with over 20,000 patients and did not find an increased incidence in all-cause mortality, major adverse cardiovascular events and venous thromboembolism in patients on these medications compared to patients in placebo or active comparator groups

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This is the single most important nutritional target on tirzepatide, more important than total calories, carbohydrate ratios, or any other macronutrient consideration

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