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They're not really a function of the dose being too high or your serum B12 level being too high

In the first enzyme reaction, methylcobalamin is used to recycle the folate cofactor 5-methyltetrahydrofolate to tetrahydrofolate thereby allowing the folate cofactor to participate in a cycle involving the biosynthesis of purines and pyrimidines

Research suggests it influences enzymatic pathways associated with telomerase activity at the molecular level

Researchers investigate these components in preclinical and in vitro work related to extracellular matrix biology, cell migration signaling, and tissue model recovery