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TMA, A forgotten uremic toxin, but not TMAO, is involved in cardiovascular pathology

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Nevertheless, the current understanding of the potential association between CM and the gut-brain axis (GBA) is based solely on indirect inferences drawn from existing literature

In animal-based models of depressive-like behavior, administration of the peptide was linked to attenuation of behavioral symptoms, indicating possible antidepressant-like activity under experimental conditions (25,26)