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Serious side effects include pancreatitis (severe abdominal pain), gallbladder disease, acute kidney injury, thyroid tumors (boxed warning), and diabetic retinopathy complications
[DOI] [PubMed] [Google Scholar] 7.Evaluating the causal effect of using glucagon-like peptide-1 receptor agonists on the risk of autoimmune diseases
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Common side effects across all semaglutide products include: Nausea Stomach pain, heartburn, diarrhea, constipation Vomiting Bloating Loss of appetite Low blood sugar Fatigue Injection site reactions (Wegovy and Ozempic) Headache Cold or flu-like symptoms Dizziness Serious side effects, though rare, may include: Allergic reactions (hives, facial/throat swelling, shortness of breath) Thyroid tumors (MTC or MEN 2): lump in neck, hoarseness, difficulty breathing or swallowing Pancreatitis: severe upper abdominal pain radiating to the back, increased heart rate, nausea Diabetic retinopathy complications: vision changes Severe hypoglycemia: sweating, blurred vision, dizziness, confusion, rapid heartbeat Kidney problems: decreased urination, thirst, dry skin Gallbladder issues: fever, claycolored stools, upper abdominal pain These are not all possible side effects
