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Description

check IGF-1 at 8 weeks | | Testosterone / TRT | Amplifies GH pulsatility | Raises IGF-1 | Monthly IGF-1 for 3 months | | Insulin (hypoglycaemia) | Glucose nadir stimulates GH | May exaggerate response | Time injection away from insulin peak | | Chronic opioids | Broad HPA and GH axis suppression | Blunts GH response | Higher dose may be needed

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Approximately 55% of children with obesity continue to have obesity in adolescence, and about 80% of adolescents with obesity remain affected by it in adulthood

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