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[2] [4] Individuals with renal impairment: According to the SmPC, Ozempic can be used without dose adjustment in patients with renal impairment, including severe impairment and end-stage renal disease

This results partly from the complexity of the fraction but also from use of different nomenclatures, based on relative electrophoretic mobilities (the major components being called 0.19, 0.28, and 0.53), solubility in chloroform:methanol (called CM1 to CM17) and subunit structure (monomeric, dimeric, and tetrameric forms occurring) (56)

While they can be harmless and occur occasionally in healthy individuals, they can also signal underlying issues that may require medical attention

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