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(2020) demonstrated that Citrus latifolia increases the production of prostaglandin F2, which acts on prostaglandin receptors to reduce the menstrual volume and inhibits the release of proinflammatory cytokines such as TNF- (Ekstrm et al., 1991)
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Specifically, PARP1 was significantly overexpressed in AILI models in vivo and in vitro, and its interaction with PXR was confirmed in immunoprecipitation and proximity biotinylation assays
