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Under physiological conditions, chaperone-mediated autophagy (CMA) degrades soluble -syn via heat shock cognate protein 70 (HSC70) recognition of KFERQ motifs and LAMP2A-mediated lysosomal transport [165]
pylori strain lacking the major Dsb oxidoreductase, encoded by hp0231 , is deficient in CagA translocation into host epithelial cells as Hp0231, among other activities, influences the structure of HopQ, an outer membrane protein that mediates pathogen adhesion to epithelial cells by interaction with CECAM receptors (Javaheri et al
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