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Studies have shown that H 2 can activate Nrf2 and induce its translocation into the nucleus, enhancing the transcription of catalase (CAT) and glutathione peroxidase 1 (GPX1) (Murakami et al., 2017), thereby upregulating the expression of intracellular antioxidant enzymes through the Nrf2-ARE pathway, neutralizing ROS, mitigating oxidative damage, and ultimately achieving systemic antioxidant protection of hydrogen at the cellular and mitochondrial levels

B.DinaO

ASTP/ONC stands for the Assistant Secretary for Technology Policy/Office of the National Coordinator on Health Information Technology

Nanocarriers as a powerful vehicle to overcome bloodbrain barrier in treating neurodegenerative diseases: Focus on recent advances