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In addition to targeting iron acquisition proteins, some efficacy has been achieved with vaccines targeting iron homeostasis in pathogens
Thus, considering the limitations encountered with animal models, like a low grade in mimicking the dose relevant sensitivities (132134), the proposed OoC system offered many advantages compared to classic in vitro or rodent models
Due to polymorphisms, gene duplication, and genetic recombination, GSTs have multiple isoenzymes with overlapping substrate specificity and diversity [200]
Hiddemann W, Buechner T, Andreeff M , Arlin Z, Gee T, Woermann B, Steinmetz J, Clarkson B
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