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Higher levels of MAOA could decrease neurotransmitter levels to maintain balanced levels of these chemicals in the brain.[ref] The MAO-A variants can interact with environmental factors to influence mental health

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Key areas of investigation include modulation of the nitric oxide (NO) system through interaction with NOS isoforms, upregulation of growth factor receptors (including VEGFR2 and EGF receptor systems), and engagement of the FAK-paxillin signaling cascade associated with cell migration and adhesion

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