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Bcl-2 Inhibition to Overcome Resistance to Chemo-and Immunotherapy

However, As-induced production of O 2 , H 2 O 2 , and MDA decreased significantly with the exogenous application of GSH to the As-stressed seedlings ( Figure 2 )

In AD, oxidative stress also plays a central role promoting A accumulation and tau phosphorylation [191] and impairing proteostasis (the homeostasis of protein folding, stability, and degradation), synaptic plasticity and other processes critical for learning and memory [188, 192]