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10.1038/nrneph.2017.107 14 Briones-HerreraA.Avila-RojasS

1c), we found an increase in the frequency of naive (T Naive ) CD4 + and CD8 + T cells, accompanied by a decrease in both central (T CM ) and effector memory (T EM ) cells in pre-symptomatic APP carriers, as compared to their age- and ethnically-matched healthy counterparts (Fig