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Description

In the specific in vitro assay measuring synaptogenesis promotion, Dihexa showed activity at picomolar concentrations far lower than concentrations needed for BDNF or other neurotrophic factors to produce comparable effects

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Moreover, attribution of direct vs indirect actions of GLP-1 is difficult, as many tissue and cellular targets of GLP-1 action do not exhibit robust or detectable GLP-1R expression

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