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9 Importantly, glutathione plays a central role in liver detoxification by helping convert fat-soluble toxins into water-soluble compounds for easier elimination

Selenium supplementation should be avoided unless deficiency is confirmed or recommended by a specialist, as excessive intake can cause selenosis (toxicity)

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PCS also induces apoptosis and autophagy by activating NF-B and MAPK signaling and increasing the phosphorylation of extracellular signal-regulated kinase (ERK), p38, and c-Jun N-terminal kinase (JNK) in HK-2 cells ( Figure 3 ) [117]