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Results You Can Expect Patients prescribed naltrexone as part of a medically supervised weight loss plan may experience: Fewer food cravings, especially for high-reward or binge foods Improved impulse control and reduced emotional eating Steady, moderate weight loss over time Better compliance with dietary and behavioral changes Enhanced results when combined with other weight loss meds Clinical studies of naltrexone (especially when combined with bupropion) show 48% total body weight loss over 612 months

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Patients generally have to wait until the medication reaches a steady state and they notice significant changes in their blood sugar levels, appetite suppression, and body weight