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You may have an underlying health condition Some underlying health conditions can make it harder to lose weight and these include: thyroid disorders, such as hypothyroidism insulin resistance, which can be caused by conditions like diabetes vitamin deficiencies hormonal imbalances, such as polycystic ovary syndrome (PCOS) depression or chronic stress How these conditions interfere with weight loss depends on the condition, but you may need a little extra time or support to lose weight

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These enhanced formulations also add the cost of the enhancer itself, though cyclodextrins are relatively inexpensive