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Rodent studies have identified thyroid C-cell changes

Clin Chim Acta 276:19 Sirtori LR, Dutra-Filho CS, Fitarelli D, Sitta A, Haeser A, Barschak AG, Wajner M, Coelho DM, Llesuy S, Bell-Klein A, Giugliani R, Deon M, Vargas CR (2005) Oxidative stress in patients with phenylketonuria

Emerging cross-kingdom evidence indicates that redox-regulated mitochondrial proteostasis and calcium-dependent stress signalling modules identified in plant systems can inform mechanistic hypotheses in mammalian neurodegeneration