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Fifth, confounding factors remain unaddresseddietary fiber (a major precursor of SCFAs) is often consumed alongside omega-3s (e.g., in fatty fish), so changes in SCFAs (24) may be driven by fiber rather than omega-3s, a confounder that was ignored in the original analysis (24, 102)

As an active area of research, it is important to note that DM2 has not only been linked to depression or anhedonia but is associated with several psychiatric disorders [13]

Hence it is mandatory to check whether the diagnosis is right or wrong