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RESULTS In ZSF1 obese rats, low-dose semaglutide in the absence of weight loss, significantly improved cardiac function, exercise tolerance, and attenuated fibrosis in the heart and liver

Zepbound is designed as a long-term treatment for chronic weight management

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Kynurenine can be metabolized via two different paths: one path produces anthranilic acid via the vitamin B 6 -dependent enzyme kynureninase, and the other path produces kynurenic acid via the kynurenine aminotransferase, which also requires vitamin B 6