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Patients should be counseled that sustainable weight management requires long-term commitment to lifestyle changes, and medication is an adjunct rather than a replacement for healthy behaviors

Anti-nausea medications like Zofran may also be helpful, and Belle Medical can provide a prescription if needed

However, overlapping primary studies were predominantly concentrated in a limited number of large-scale, frequently cited RCTs in the field of GLP-1 RAs-such as LEADER, SUSTAIN, EXSCEL, HARMONY Outcomes, REWIND, ELIXA, SELECT, PIONEER, AWARD, AMPLITUDE, LEAD, SCALE, and STEP