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The degree of liver steatosis was assessed semiquantitatively as the percentage as the percentage of the total evaluated area occupied by lipid droplets

When used as part of a broader weight management strategy, including diet, exercise, and lifestyle adjustments, these medications have been shown to be safe and effective for extended periods, with mild side effects like nausea typically diminishing over time

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A separate Phase 2 sub-study published in 2024 in Nature Medicine looked specifically at participants with non-alcoholic fatty liver disease (NAFLD) a condition where fat accumulates in the liver and can progress to serious disease