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0.1% (placebo) Steady State: Achieved after 4-5 weeks of weekly dosing Safety: Nausea (68% at 4.5 mg), vomiting (32%), generally mild-moderate and transient Discontinuation: 14% discontinued due to GI adverse events Appetite Effects: Significant reductions in Visual Analogue Scale (VAS) hunger scores Publication: Lau DCW, et al

Once in the central nervous system, it modulates neurotransmitters like dopamine and serotonin, which are crucial for mood, attention, and memory

The benzyl alcohol inhibits bacterial growth, which means that a reconstituted vial can, in principle, be used across multiple doses over a period of days to weeks rather than being discarded after a single use as would be required with plain sterile water