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GLP-1RAs stimulate insulin secretion and suppress glucagon secretion, which may modify cardiac energy metabolism in T2DM patients [103]

The longer acting GLP-1 receptor agonists are more effective than the shorter acting forms at reducing HbA 1c and fasting glucose levels, whereas the shorter acting forms are more effective at reducing postprandial glucose levels [3]

Once enrolled, adult patients in the EMPA-REG OUTCOME, EMPEROR-Reduced, EMPEROR-Preserved, and EMPA-KIDNEY trials were not required to discontinue therapy for worsening of eGFR to less than 20 mL/min/1.73 m2 or initiation of dialysis [see Clinical Studies (14.3, 14.4, 14.5)]

each 10 mg vial typically uses 3.0 mL