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This dual mechanism is why tirzepatide has produced greater weight loss in clinical trials than single-agonist GLP-1 drugs like semaglutide

Practical Strategies to Reduce Nausea and Stomach Upset Eating smaller, more frequent mealsespecially lower-fat, less dense foodshelps your stomach process food more smoothly while you're taking a GLP-1 medication

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Consult Your Doctor: If fatigue persists, discuss it with your doctor promptly