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Interestingly, in a pilot study, exposure of autologous glioma cells treated ex vivo with IGF-1R antisense oligos induced partial tumour regression in some patients with malignant astrocytoma (Andrews et al, 2001)

J Biol Chem 292:1680416809 Zorov DB, Filburn CR, Klotz LO, Zweier JL, Sollott SJ (2000) Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes

The inclusion criteria included publications published in the previous decade, and the search approach was iterative, with continual refinement based on the identified literature until a thorough selection of relevant studies was obtained

Eso es porque la grasa debe llegar primero a las mitocondrias, la fuente de energa de las clulas de su cuerpo