However, elevated iron levels can disrupt mitochondrial iron homeostasis (Steiner and Lang, 2017
For instance, if you dissolve 5 mg of a peptide in 100 microliters of DMSO, you must dilute that stock at least 1:1000 in your final experimental medium to stay in the safe zone
analyzed by HS-AFM structural dynamics of intrinsically disordered, barrier-forming phenylalanine-glycine nucleoporins (FG Nups) within the nuclear pore complexes (NPCs) from the Xenopus laevis oocyte and showed that FG Nups are highly flexible and dynamically fluctuating chains that rapidly elongate and retract, consistent with the diffusive motion of tethered polypeptide chains (Sakiyama et al., 2016)
Advances in quantitative redox proteomic techniques, which are able to differentiate between various thiol modifications, in addition to improvements in the detection via mass spectrometry of low-abundance proteins, have recently stimulated significant research in protein supersulfidation [71,72]