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[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Do KQ, Cabungcal JH, Frank A, Steullet P, Cuenod M

Regarding DPP-4 inhibitors, sitagliptin was associated with the highest number of adverse events across the top five SMQs, indicating the greatest potential risk

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When the pharmacological appetite suppression is reduced or withdrawn, the caloric threshold required to maintain their new weight is lower than expected, but their appetite, shaped by the neurological reward pathways that GLP-1s modulate, does not stay suppressed indefinitely without ongoing treatment