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Similar recommendations were made by the European Medicines Agency (EMA) that required including major adverse cardiovascular events (MACE) as a primary endpoint ( These regulatory requirements led to the discovery of cardiovascular benefits in GLP-1R agonists, demonstrating the importance of due diligence and proactive safety monitoring

And so again, thats kind of what we saw is that the tendons were smaller because of the GLP-1s, and they didnt shrink further with the immobilization