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An antioxidant is a substance that prevents or slows oxidative damage in cells by neutralising free radicals or other reactive oxygen species, thereby protecting biological molecules such as DNA, proteins, and lipids from oxidation

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The changes in biological metabolites (e.g., iron and lipids) support ferroptosis as a potential therapeutic strategy for RCC, while iron metabolism and ferroptosis regulation have been examined as anti-RCC agents in numerous studies, and various ferroptosis-related molecules have been shown to be related to the metastasis and prognosis of ccRCC