Its primary mechanisms include promoting angiogenesis (new blood vessel formation) through VEGF upregulation, modulating the nitric oxide system in a context-dependent manner, activating the FAK-paxillin pathway to drive cell migration and tissue rebuilding, and regulating multiple growth factors (PDGF, TGF-beta, FGF) involved in organized tissue repair
Acta , 738 , 203-217, Alfthan, G., Xu, G
The functional impact of these abundance and localization changes were determined with pulse chase experiments using labeled metabolic substrates, bioenergetics, and metabolite quantification
Community sources describe improved joint comfort, attributed to GH-mediated increases in synovial fluid production and cartilage support