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Separating pain medication doses from semaglutide by 24 hours minimizes this effect, and your prescriber can recommend specific timing strategies based on your pain condition and dosing schedule

It produces more modest results than semaglutide or tirzepatide, typically around 8 percent body weight loss, but it was the first GLP-1 to receive FDA approval specifically for weight management and remains a viable option for patients who prefer a shorter-acting medication or who experience intolerable side effects on the more potent formulations

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