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The mechanisms promoting drug resistance include the following: first, at the pharmacokinetic level, the overactivation of drug efflux pumps is mediated by ATP-binding cassette transporters (ABC transporters)

Back pain can certainly cause anxiety, depression, and catastrophizing thoughts

Peptides can have structures similar to those of certain hormones and signaling compounds in the body, allowing them to engage with and activate multiple receptors throughout the body, thereby influencing various bodily processes

73 GSH is not commercially available as an oral or injectable product in the US because of pharmaceutical problems, including poor oral bioavailability and a short halflife (2 min) with intravenous administration