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and (c) activating AMP-activated protein kinase (AMPK) within the nucleus tractus solitarius (NTS), which mediates the anorexigenic effect of GLP-1 receptor agonism [12]

KEY TAKEAWAYS BY PRODUCT Ozempic dominated the GLP-1 agonists market owing to its high adoption for the management of type 2 diabetes, wide geographic availability, and a strong brand recognition

2023;46(Suppl 1):S97-s110

70 A systematic review of 22 studies investigated the effect of intentional weight loss in overweight and obese patients with HF and demonstrated that all forms of weight loss (lifestyle changes, pharmacotherapy or bariatric surgery) are likely to result in significant improvements of symptoms and HRQoL in HF patients