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Absolute contraindications Medullary thyroid cancer MEN-2 Pregnancy or breastfeeding Prior severe allergic reaction to GLP-1 medications Conditions requiring extra caution Gastroparesis or delayed gastric emptying History of pancreatitis Advanced diabetic retinopathy Use alongside medications that increase hypoglycemia risk These and a few other situations require individualized assessment, which is why specialty endocrine care matters

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[DOI] [PubMed] [Google Scholar] 68.Mohyeddin Bonab M, Ali Sahraian M, Aghsaie A, Ahmadi Karvigh S, Massoud Hosseinian S, Nikbin B

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However, a few commenters noted possible challenges around licensing, data sources, and inequitable scoring if a PRO-PM is implemented

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"The GLP-1 market is very dynamic, but it's clear employers are working to expand coverage for their employees," says PCMA spokesperson Greg Lopes

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