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It is worth noticing that the types of COVID-19 vaccinations that most frequently cause adverse effects on thyroid function are mRNA-based vaccines, followed by adenovirus-vectored SARS-CoV-2 vaccines and inactivated vaccines (134)

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Transition from acute to chronic inflammation is orchestrated by sustained production of cytokines (e.g., TNF-, IL-1, IL-6, CXCL8), continuous activation of macrophages, neutrophils, and T cells, defective resolution programmes, tissue remodelling driven by transforming growth factor-, and altered cell-death pathways

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