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This means the indirect UTI risk factors related to dehydration from GI symptoms also decrease over time

This requires robust, sustained pharmacovigilance systems capable of detecting and managing long-term and low-frequency adverse events

Nausea affected up to about 29 percent of participants Diarrhea up to about 23 percent Vomiting up to about 13 percent in some studies Reports of sleep disturbance or insomnia were not prominent in the trial safety tables for Zepbound