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Moreover, while oral drugs need to be stable enough to survive the enzymatic degradation in the stomach and liver, IN-delivered drugs face fewer challenges due to the relatively lower expression of enzymes in the nasal mucosa

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These symptoms arise primarily from slowed gastric emptying and altered gut motility

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Carnitine deficiency in autism: Mutations in enzymes involved in carnitine biosynthesis have been linked to autism spectrum disorders, indicating a broader systemic impact of carnitine beyond fertility

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What makes tirzepatide fundamentally different is that it doesnt just act on GLP-1it also targets GIP, a second incretin hormone with distinct effects

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