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Specifically, adding 5-amino-1mq (30 M and above) to C2C12 myoblast cultures (a common in vitro myoblast model) markedly upregulates the expression of myogenic marker genes, including myosin heavy chain (MyHC), actin, and myogenin (MyoG)

There is also a reason the combination is difficult to test cleanly: because both compounds act on overlapping repair pathways (angiogenesis, cell migration), a study of the two together struggles to attribute any observed effect to either one