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The dominant self-reported pattern

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Never start, stop, or modify your dosage without first consulting your prescribing physician

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This evidence relates to the branded, FDA-reviewed formulation studied in those trials and does not establish safety, effectiveness, or equivalence for compounded formulations, which are not FDA-approved finished products and may differ in concentration, excipients, and pharmacy-specific preparation

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The SURMOUNT-5 clinical trial directly compared tirzepatide (Zepbound) to semaglutide (Wegovy) over 72 weeks at their maximum tolerated doses

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