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This risk is often dose-dependent and may be influenced by genetic predisposition, lifestyle factors, and interactions with other medications

Both medications can influence how your body manages blood sugar

Additional functions include 9,10 : Balancing blood pH Facilitating the conversion of vitamin D into its active form (ie, 1,25-dihydroxycholicalciferol) Producing hormones that help control blood pressure and red blood cell production Maintaining normal blood concentrations of electrolytes (eg, potassium, sodium, phosphorus, and calcium) Kidney damage and the loss of function may gradually lead to CKD

Although gut-bone axis remains the gold standard, future directions need to focus on more complicated multi-systems