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If you're not getting enough B12, you can experience anemia, fatigue, weakness, constipation, decreased appetite, weight loss, dizziness, lightheadedness, confusion, poor memory, soreness of your tongue and mouth, and tingling and numbness in your hands and feet, according to Harvard Health Publishing

The most commonly affected area is the terminal ileum (ileitis or regional enteritis), but the disease frequently extends into the colon (ileocolitis)