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Reduction of Hyperinsulinaemia and IGF-1 Signalling Elevated circulating insulin and insulin-like growth factor-1 (IGF-1) represent well-established promoters of tumour cell proliferation
Because of semaglutide and tirzepatide shortages, which have forced patients to involuntarily stop and restart treatment, reliable data on adherence for GLP-1s is not yet available
In another study, a 12-week combination therapy showed greater vascular and myocardial function improvement, particularly in those with impaired left ventricular (LV) function [12]
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