To enhance therapeutic efficacy and minimize risks, future research should explore selective targeting of TNFR1 or activation of the TNF/TNFR2 pathway, which may provide a safer and more effective means of suppressing inflammation (95)
Vascular Health and Risk Management, 1 (3), 183198
Importantly, the observed LBM reduction has not consistently translated into functional impairment, and emerging evidence suggests that GLP-1 RAs may counterbalance this effect by improving muscle quality and metabolism [21]
Then, the total number of cells (DAPI or NucBlue Live positive, blue), the number of apoptotic cells (CellEvent Caspase-3/7 positive, green) and dead cells (PI positive, red, or both CellEvent Caspase-3/7 and PI positive, yellow, or NucGreen positive, green) were counted