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Research has shown that GHK Cu: Downregulates TGF-beta1 (the primary pro-fibrotic cytokine) in fibrotic cell models Upregulates decorin a proteoglycan that inhibits TGF-beta1 signalling and organises collagen fibril structure Reduces expression of MMP inhibitors, allowing physiological matrix remodelling to proceed This dual action promoting organised collagen synthesis in healing wounds while suppressing dysregulated fibrotic collagen makes GHK Cu of interest in research models of skin fibrosis, liver fibrosis, and lung fibrosis

Antimicrobial Activity: In vitro (test tube) studies have shown KPV exhibits activity against specific bacteria and fungi (including C albicans)

Made with poly-L-lactic acid, Sculptra gradually encourages new collagen growth, resulting in firmer, smoother skin that appears more youthful over time

Different countries have unique medication rules