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Vita PM, Restelli A, Caspani P, et al

To identify pneumonia-associated metabolic biomarkers, untargeted metabolomics was conducted on the serum, and a total of 755 polar metabolites and lipids were detected and identified (Supplementary Table S2 )

In mitapivat-treated 4.2 / mice, we noted decreased protein oxidation in liver as determined by Oxyblot (Figure 5C and Supplemental Figure 8B), which was accompanied by blunted activation of Nrf2 and NF-B p65 (Figure 5D and Supplemental Figure 8C) with resultant downregulation of Nrf2-related cytoprotectors such as heme-oxygenase-1 (HO-1) and Gpx1 (Figure 5E and Supplemental Figure 8D) (17, 46, 47)

It does not imply that the treatment has been endorsed, recommended, or approved as an aesthetic procedure by MOH or HSA