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47 Conclusion Management of SCD is complex and multifactorial

Highly conserved across plants, animals and fungi, the glutathione system helps maintain and restore redox balance, and preserve mitochondrial function and metabolic flexibility

Similarly, another study demonstrated nephrotoxicity in colitis mice treated with green tea extract containing 35% EGCG, evidenced by increased serum creatinine levels (a nephropathy biomarker), and elevated expression of antioxidant enzymes (HO-1 and NQO1) and HSP 90 (238)