Always inform your GP or pharmacist about any additional medications or supplements you're considering, as interactions are possible
The trials included individuals with overweight (BMI 27 kg/m 2 ) and 1 weight-related complication, including dyslipidaemia, hypertension, sleep apnoea, impaired glucose tolerance and/or impaired fasting glucose and type 2 diabetes, or individuals with obesity (BMI 30 kg/m 2 ) with or without complications
Infertility or recurrent miscarriage [5] Understanding MTHFR Gene Variants Two well-documented MTHFR polymorphisms have significant clinical implications: C677T Variant (rs1801133): Homozygous individuals may experience a 70% reduction in enzyme activity , leading to increased homocysteine levels and an elevated risk of cardiovascular disease, miscarriage, and neural tube defects [4]
Notably, blurred vision, retinopathy, and other macular complications were defined as exploratory outcomes that warrant additional research to better understand all risks of taking the medication
