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In vivo , patient-derived xenografts (PDXs) and syngeneic mouse models have also demonstrated that CPEB3 depletion inhibits tumour growth and metastasis, as well as facilitating pharmacokinetics, bioavailability and lack of systemic toxicity evaluations prior to human testing which are invaluable safety and efficacy details (222)

Mainstream medical bodies often call for larger, randomized controlled trials to definitively prove causation, but the high correlation remains a vital piece of the puzzle for functional medicine practitioners treating complex chronic illness