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Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with MOUNJARO [see Contraindications (4) and Warnings and Precautions (5.1)]

Some researchers hypothesize that the increased energy expenditure from glucagon activation means less of the caloric deficit needs to come from dietary restriction, which may be less catabolic to muscle tissue

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